18 Hotels in Santa Fe, TX

Comfort Inn & Suites
10700 Emmett F. Lowry Expwy,
Texas City, TX, 77591, US
4.99 mi from Santa Fe, TX
2.5 stars rating. Fair. 356 reviews2.5 stars rating. Fair. 356 reviews
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Strikethrough Rate:~~$120~~Discounted rate:$103USD/night
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Quality Inn Texas City I-45
2320 FM 2004,
Texas City, TX, 77591, US
5.01 mi from Santa Fe, TX
3.52 stars rating. Good. 443 reviews3.52 stars rating. Good. 443 reviews
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Strikethrough Rate:~~$129~~Discounted rate:$123USD/night
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Comfort Suites near NASA - Clear Lake
16931 N. Texas Ave,
Webster, TX, 77598, US
11.46 mi from Santa Fe, TX
3.89 stars rating. Good. 1134 reviews3.89 stars rating. Good. 1134 reviews
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Strikethrough Rate:~~$130~~Discounted rate:$124USD/night
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MainStay Suites Houston NASA/Clear Lake
1050 Bay Area Blvd,
Houston, TX, 77058, US
12.26 mi from Santa Fe, TX
3.37 stars rating. Good. 90 reviews3.37 stars rating. Good. 90 reviews
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Strikethrough Rate:~~$99~~Discounted rate:$94USD/night
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Quality Inn & Suites Seabrook- NASA- Kemah
2720 Nasa Parkway,
Seabrook, TX, 77586, US
13.23 mi from Santa Fe, TX
4.38 stars rating. Excellent. 1174 reviews4.38 stars rating. Excellent. 1174 reviews
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Strikethrough Rate:~~$127~~Discounted rate:$114USD/night
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Comfort Suites La Porte - Baytown
902 South 8th Street,
La Porte, TX, 77571, US
19.61 mi from Santa Fe, TX
4.21 stars rating. Excellent. 661 reviews4.21 stars rating. Excellent. 661 reviews
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Strikethrough Rate:~~$95~~Discounted rate:$77USD/night
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Rodeway Inn South Houston
2042 Houston Blvd.,
South Houston, TX, 77587, US
20.45 mi from Santa Fe, TX
2.94 stars rating. Fair. 116 reviews2.94 stars rating. Fair. 116 reviews
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Strikethrough Rate:~~$59~~Discounted rate:$56USD/night
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Comfort Suites Deer Park Pasadena
1501 Center St.,
Deer Park, TX, 77536, US
22.08 mi from Santa Fe, TX
3.97 stars rating. Good. 562 reviews3.97 stars rating. Good. 562 reviews
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Strikethrough Rate:~~$87~~Discounted rate:$74USD/night
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Comfort Suites
3606 89th Street,
Galveston, TX, 77554, US
17.54 mi from Santa Fe, TX
3.48 stars rating. Good. 1652 reviews3.48 stars rating. Good. 1652 reviews
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Strikethrough Rate:~~$259~~Discounted rate:$246USD/night
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Sleep Inn & Suites Galveston Island
6628 Broadway Street,
Galveston, TX, 77554, US
16.78 mi from Santa Fe, TX
2.96 stars rating. Fair. 826 reviews2.96 stars rating. Fair. 826 reviews
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Strikethrough Rate:~~$199~~Discounted rate:$189USD/night
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Quality Inn & Suites Galveston - Beachfront
5924 Seawall Blvd.,
Galveston, TX, 77551, US
18.59 mi from Santa Fe, TX
4.04 stars rating. Very Good. 3087 reviews4.04 stars rating. Very Good. 3087 reviews
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Strikethrough Rate:~~$310~~Discounted rate:$279USD/night
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Comfort Inn & Suites
2818 Avenue R 1 2,
Galveston, TX, 77550, US
19.84 mi from Santa Fe, TX
3.14 stars rating. Good. 183 reviews3.14 stars rating. Good. 183 reviews
$239USD/night
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Econo Lodge Galveston Seawall
3008 Seawall Blvd,
Galveston, TX, 77550-7677, US
19.79 mi from Santa Fe, TX
2.76 stars rating. Fair. 101 reviews2.76 stars rating. Fair. 101 reviews
$200USD/night
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Sleep Inn & Suites Pearland - Houston South
1908 Country Place Parkway,
Pearland, TX, 77584, US
21.64 mi from Santa Fe, TX
3.97 stars rating. Good. 647 reviews3.97 stars rating. Good. 647 reviews
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Strikethrough Rate:~~$105~~Discounted rate:$95USD/night
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Quality Suites Houston Hobby Airport
7775 Airport Blvd,
Houston, TX, 77061, US
21.99 mi from Santa Fe, TX
3.95 stars rating. Good. 201 reviews3.95 stars rating. Good. 201 reviews
$81USD/night
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Quality Inn Pasadena - Houston East
114 S. Richey St.,
Pasadena, TX, 77506, US
23.99 mi from Santa Fe, TX
3.84 stars rating. Good. 309 reviews3.84 stars rating. Good. 309 reviews
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Strikethrough Rate:~~$89~~Discounted rate:$85USD/night
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Seabreeze Hotel, Ascend Hotel Collection
2311 Avenue P 1 2,
Galveston, TX, 77550, US
20.02 mi from Santa Fe, TX
No Reviews YetNo Reviews Yet
Coming soonStart booking 02 jun 2026
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Comfort Suites Seabrook - Kemah
5755 Bayport Blvd,
Seabrook, TX, 77586, US
15.44 mi from Santa Fe, TX
3.42 stars rating. Good. 219 reviews3.42 stars rating. Good. 219 reviews
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Good to know

Number of hotels

18 hotels in Santa Fe

Highest Price

$279

Lowest Price

$56

Avg. rating

16 hotels near Santa Fe, TX

Comfort Inn & Suites

Quality Inn Texas City I-45

Comfort Suites near NASA - Clear Lake

MainStay Suites Houston NASA/Clear Lake

Quality Inn & Suites Seabrook- NASA- Kemah

Comfort Suites La Porte - Baytown

Rodeway Inn South Houston

Comfort Suites Deer Park Pasadena

Comfort Suites

Sleep Inn & Suites Galveston Island

Quality Inn & Suites Galveston - Beachfront

Comfort Inn & Suites

Econo Lodge Galveston Seawall

Sleep Inn & Suites Pearland - Houston South

Quality Suites Houston Hobby Airport

Quality Inn Pasadena - Houston East

Change your dates to book properties below.

Seabreeze Hotel, Ascend Hotel Collection

Comfort Suites Seabrook - Kemah

Other Santa Fe searches

Good to know

18 hotels in Santa Fe

$279

$56

3.4 (11761 reviews)

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