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Comfort Inn & Suites Santee I-95

3.92 stars rating. Good.

1720 reviews

3.92 stars rating. Good. 1720 reviews
Amenities
4.4
Cleanliness
4.1
Property Condition
4.4
Safety & Security
4.6
Staff Service
4.3
Value
4.2
Sold Out
Tue, Jul 29, 2025 to Wed, Jul 30, 2025
Sold Out
Tue, Jul 29, 2025 to Wed, Jul 30, 2025

Modern yet cozy hotel puts you near Lake Marion and other outdoor fun

If your idea of a vacation or getaway involves lakes, golf, hiking and sunshine you’ve found the perfect option. Of course, we can’t guarantee the sunshine. But we can guarantee proximity to the three other things with modern amenities and cozy accommodations with the Comfort Inn & Suites® in Santee, SC. The hotel is near the shores of Lake Marion and everything it has to offer. You’ll also be nestled between the Lake Marion Golf Course and the Santee National Golf Course. About 5 miles down the road is the Santee State Park. For trail biking and hiking, you can easily connect to the Palmetto Trail, a 500-mile path across the state.

Highlights

  • Free WiFi
  • Free Hot Breakfast
  • Vending Machines*
  • Seasonal Outdoor Pool
  • Surveillance Security
  • Check in / out3:00 PM / 11:00 AM

*May require an additional cost

Guest Rooms

Available Guest Rooms

  • Earn Choice Privileges Points*

Loading available rooms

Amenities

Featured Amenities(19)

  • Free WiFi
  • Free Hot Breakfast
  • Vending Machines*
  • Seasonal Outdoor Pool
  • Surveillance Security
  • Exercise Room
  • Free Accessible Parking
  • Government Travelers: FEMA Approved
  • Copy Machine*

*May require an additional cost

Reviews

Guest Reviews

(1720 reviews)
3.9/5

76% guests recommend this hotel

Amenities
4.4
Cleanliness
4.1
Property Condition
4.4
Safety & Security
4.6
Staff Service
4.3
Value
4.2
5 stars rating. Exceptional. 1 review
5/5

The staff are personable and helpful. The rooms are clean and comfortable. And the breakfast buffet is nice.

Verified Guest
July 2025

Verified

5 stars rating. Exceptional. 1 review
5/5

Great people, equally great service

Great people fantastic service

Verified Guest
July 2025

Verified

4 stars rating. Very Good. 1 review
4/5

Santee Stay

The hotel was clean and cool. However I think the No Smoking signs for inside hotel need to be posted better because there were people smoking all night in the rooms both nights I stayed. Being an X smoker of 21 years I can smell a cig a mile away

Verified Guest
July 2025

Verified