Live like home when you stay at the new MainStay Suites^® Carlisle - Harrisburg hotel. With a convenient location off Interstate 81, our all-suite hotel just 10 minutes from downtown Carlisle, where you'll find an array of restaurants, retail shops, antique stores and art galleries. We're also close to top Cumberland County employers, businesses, attractions and outdoor activities. The state capital of Harrisburg is around a 30-minute drive away.