Comfort Inn & Suites^® Springfield I-44  hotel is conveniently located off the freeway near Springfield-Branson National Airport, the downtown airport and Missouri State University-Springfield. We welcome business travelers and accommodate your needs with our business center, meeting space and room work desks. If you’re in Missouri’s third largest city for fun, you’ll have a great home base for relaxing at the end of a busy day of sightseeing. Our suites, which are 25 percent larger than the traditional hotel room, feature cozy beds, refrigerators, microwaves and free WiFi.